Fernández, Jorge, Bruneau, Nicole, Fasce, Rodrigo, Martín, Héctor San, Balanda, Monserrat, Bustos, Patricia, Ulloa, Soledad, Mora, Judith, Ramírez, Eugenio |
Neutralization of alpha, gamma, and D614G SARS-CoV-2 variants by CoronaVac vaccine-induced antibodies |
Vaccination generates a neutralizing immune response against SARS-CoV-2. The genomic surveillance is showing the emergence of variants with mutations in spike, the main target of neutralizing antibodi... |
2022 |
94 |
Ver Más |
Quezada-Aguiluz, Mario, Opazo-Capurro, Andrés, Lincopan, Nilton, Esposito, Fernanda, Fuga, Bruna, Mella-Montecino, Sergio, Riedel, Gisela, Lima, Celia A., Bello-Toledo, Helia, Cifuentes, Marcela, Silva-Ojeda, Francisco, Barrera, Boris, Hormazábal, Juan C., González-Rocha, Gerardo |
Novel Megaplasmid Driving NDM-1-Mediated Carbapenem Resistance in Klebsiella pneumoniae ST1588 in South America |
Carbapenem-resistant Enterobacterales (CRE) is a critical public health problem in South America, where the prevalence of NDM metallo-betalactamases has increased substantially in recent years. In thi... |
2022 |
11 |
Ver Más |
Quezada-Aguiluz, Mario, Aguayo-Reyes, Alejandro, Carrasco, Cinthia, Mejías, Daniela, Saavedra, Pamela, Mella-Montecinos, Sergio, Opazo-Capurro, Andrés, Bello-Toledo, Helia, Munita, José M., Hormazábal, Juan C., González-Rocha, Gerardo |
Phenotypic and Genotypic Characterization of Macrolide, Lincosamide and Streptogramin B Resistance among Clinical Methicillin-Resistant Staphylococcus aureus Isolates in Chile |
Macrolides, lincosamides, and type B streptogramins (MLSB) are important therapeutic options to treat methicillin-resistant Staphylococcus aureus (MRSA) infections, however, resistance to these antibi... |
2022 |
11 |
Ver Más |
Hott-Schulz, Karla, Ramírez-Villalobos, Eugenio, Ortega-Peña, Macarena, Santander-Cabello, Ester, Fernández-Moraga, Javier, Zemelman-Decarli, Viviana, Correa-Soza, Claudia |
Prevalence and genotypes of cervical and vaginal HPV in female sex workers attending a Sexual Control Centre, North Area of Santiago, Chile] |
BACKGROUND: In Chile, cervical cancer is the second leading cause of death from malignancy in women. The main causal agent of cervical cancer is the human papillomavirus (HPV). Compared with the gener... |
2022 |
39 |
Ver Más |
Díaz-Dinamarca, Diego A., Salazar, Michelle L., Castillo, Byron N., Manubens, Augusto, Vasquez, Abel E., Salazar, Fabián, Becker, María Inés |
Protein-Based Adjuvants for Vaccines as Immunomodulators of the Innate and Adaptive Immune Response: Current Knowledge, Challenges, and Future Opportunities |
New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic than classical vaccines formulated with live-attenuated or inactivated pathogens. This difference has led to an... |
2022 |
14 |
Ver Más |
Pidal, Paola, Fernández, Jorge, Airola, Constanza, Araujo, Miguel, Menjiba, Ana María, Martín, Héctor San, Bruneau, Nicole, Balanda, Monserrat, Elgueta, Coral, Fasce, Rodrigo, Valenzuela, María Teresa, Orellana, Ariel, Ramírez, Eugenio |
Reduced neutralization against Delta, Gamma, Mu, and Omicron BA.1 variants of SARS-CoV-2 from previous non-Omicron infection |
The understanding of the host immune response to SARS-CoV-2 variants of concern is critical for improving diagnostics, therapy development, and vaccines. Here, we analyzed the level of neutralizing an... |
2022 |
|
Ver Más |
Bueno S.M., Abarca K., González P.A., Gálvez N.M.S., Soto J.A., Duarte L.F., Schultz B.M., Pacheco G.A., González L.A., Vázquez Y., Ríos M., Melo-González F., Rivera-Perez D., Iturriaga C., Urzúa M., Domínguez A., Andrade C.A., Berríos-Rojas R.V., Canedo-Marroquín G., Covián C., Moreno-Tapia D., Saavedra F., Vallejos O.P., Donato P., Espinoza P., Fuentes D., González M., Guzmán P., Muñoz Venturelli P., Perez C.M., Potin M., Rojas Á., Fasce R.A., Fernández J., Mora J., Ramírez E., Gaete-Argel A., Oyarzún-Arrau A., Valiente-Echeverría F., Soto-Rifo R., Weiskopf D., Sette A., Zeng G., Meng W., González-Aramundiz J.V., Kalergis A.M. |
Safety and Immunogenicity of an Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Subgroup of Healthy Adults in Chile |
Background: The development of effective vaccines against coronavirus disease 2019 is a global priority. CoronaVac is an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccin... |
2022 |
75 |
Ver Más |
de Almeida L.M., Cortés S., Vilensky M., Valenzuela O., Cortes-Sanabria L., de Souza M., Barbeito R.A., Abdelhay E., Artagaveytia N., Daneri-Navarro A., Llera A.S., Müller B., Podhajcer O.L., Velazquez C., Alcoba E., Alonso I., Bravo A.I., Camejo N., Carraro D.M., Castro M., Cataldi S., Cayota A., Cerda M., Colombo A., Crocamo S., Del Toro-Arreola A., Delgadillo-Cristerna R., Delgado L., Breitenbach M.D., Fernández E., Fernández J., Fernández W., Franco-Topete R.A., Gaete F., Gómez J., Gonzalez-Ramirez L.P., Guerrero M., Gutierrez-Rubio S.A., Jalfin B., Lopez-Vazquez A., Loria D., Míguez S., Moran-Mendoza A.D.J., Morgan-Villela G., Mussetti C., Nagai M.A., Oceguera-Villanueva A., Reis R.M., Retamales J., Rodriguez R., Rosales C., Salas-Gonzalez E., Segovia L., Sendoya J.M., Silva-Garcia A.A., Viña S., Zagame L., Jones B., Szklo M., United States-Latin American Cancer Research Network (US-LACRN) |
Socioeconomic, Clinical, and Molecular Features of Breast Cancer Influence Overall Survival of Latin American Women |
Molecular profile of breast cancer in Latin-American women was studied in five countries: Argentina, Brazil, Chile, Mexico, and Uruguay. Data about socioeconomic characteristics, risk factors, prognos... |
2022 |
12 |
Ver Más |
Llera A.S., Abdelhay E.S.F.W., Artagaveytia N., Daneri-Navarro A., Müller B., Velazquez C., Alcoba E.B., Alonso I., Alves da Quinta D.B., Binato R., Bravo A.I., Camejo N., Carraro D.M., Castro M., Castro-Cervantes J.M., Cataldi S., Cayota A., Cerda M., Colombo A., Crocamo S., Del Toro-Arreola A., Delgadillo-Cisterna R., Delgado L., Dreyer-Breitenbach M., Fejerman L., Fernández E.A., Fernández J., Fernández W., Franco-Topete R.A., Gabay C., Gaete F., Garibay-Escobar A., Gómez J., Greif G., Gross T.G., Guerrero M., Henderson M.K., Lopez-Muñoz M.E., Lopez-Vazquez A., Maldonado S., Morán-Mendoza A.J., Nagai M.A., Oceguera-Villanueva A., Ortiz-Martínez M.A., Quintero J., Quintero-Ramos A., Reis R.M., Retamales J., Rivera-Claisse E., Rocha D., Rodríguez R., Rosales C., Salas-González E., Sanchotena V., Segovia L., Sendoya J.M., Silva-García A.A., Trinchero A., Valenzuela O., Vedham V., Zagame L., Podhajcer O.L., United States-Latin American Cancer Research Network (US-LACRN) |
The Transcriptomic Portrait of Locally Advanced Breast Cancer and Its Prognostic Value in a Multi-Country Cohort of Latin American Patients |
Purposes: Most molecular-based published studies on breast cancer do not adequately represent the unique and diverse genetic admixture of the Latin American population. Searching for similarities and ... |
2022 |
12 |
Ver Más |
Oyarte, Marcela, Cabieses, Baltica, Rada, Isabel, Blukacz, Alice, Espinoza, Manuel, Mezones-Holguin, Edward |
Unequal Access and Use of Health Care Services among Settled Immigrants, Recent Immigrants, and Locals: A Comparative Analysis of a Nationally Representative Survey in Chile |
Globally, and particularly in the Latin American region, international migration continues to grow. Access and use of health care services by migrants vary according to their country of origin and res... |
2022 |
20 |
Ver Más |
Maes, Mailis, Sikorski, Michael J., Carey, Megan E., Higginson, Ellen E., Dyson, Zoe A., Fernandez, Alda, Araya, Pamela, Tennant, Sharon M., Baker, Stephen, Lagos, Rosanna, Hormazábal, Juan Carlos, Levine, Myron M., Dougan, Gordon |
Whole genome sequence analysis of Salmonella Typhi provides evidence of phylogenetic linkage between cases of typhoid fever in Santiago, Chile in the 1980s and 2010-2016 |
Typhoid fever epidemiology was investigated rigorously in Santiago, Chile during the 1980s, when Salmonella enterica serovar Typhi (S. Typhi) caused seasonal, hyperendemic disease. Targeted interventi... |
2022 |
16 |
Ver Más |
Moretti Anfossi, Christian, Ahumada Muñoz, Magdalena, Tobar Fredes, Christian, Pérez Rojas, Felipe, Ross, Jamie, Head, Jenny, Britton, Annie |
Work Exposures and Development of Cardiovascular Diseases: A Systematic Review |
INTRODUCTION: Cardiovascular diseases (CVDs) are the number one cause of death, and there is evidence that work exposures could be associated with their development. This study aimed to systematically... |
2022 |
66 |
Ver Más |
Imambocus, Bibi Nusreen, Zhou, Fangmin, Formozov, Andrey, Wittich, Annika, Tenedini, Federico M., Hu, Chun, Sauter, Kathrin, Macarenhas Varela, Ednilson, Herédia, Fabiana, Casimiro, Andreia P., Macedo, André, Schlegel, Philipp, Yang, Chung-Hui, Miguel-Aliaga, Irene, Wiegert, J. Simon, Pankratz, Michael J., Gontijo, Alisson M., Cardona, Albert, Soba, Peter |
A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae |
Animals display selective escape behaviors when faced with environmental threats. Selection of the appropriate response by the underlying neuronal network is key to maximizing chances of survival, yet... |
2021 |
|
Ver Más |
Canals, Mauricio, Canals, Andrea, Ayala, Salvador, Valdebenito, Jorge, Alvarado, Sergio, Cáceres, Dante |
Changes in Age and Geographic Distribution of the Risk of Chagas Disease in Chile from 1989 to 2017 |
The interruption of vector-borne transmission of Chagas disease was certified in Chile in 1999. Our goal was to determine the effects of the interruption of vector transmission on the age and spatial ... |
2021 |
21 |
Ver Más |
Bennett, Julia C., Hetrich, Marissa K., Garcia Quesada, Maria, Sinkevitch, Jenna N., Deloria Knoll, Maria, Feikin, Daniel R., Zeger, Scott L., Kagucia, Eunice W., Cohen, Adam L., Ampofo, Krow, Brandileone, Maria-Cristina C., Bruden, Dana, Camilli, Romina, Castilla, Jesús, Chan, Guanhao, Cook, Heather, Cornick, Jennifer E., Dagan, Ron, Dalby, Tine, Danis, Kostas, de Miguel, Sara, De Wals, Philippe, Desmet, Stefanie, Georgakopoulou, Theano, Gilkison, Charlotte, Grgic-Vitek, Marta, Hammitt, Laura L., Hilty, Markus, Ho, Pak-Leung, Jayasinghe, Sanjay, Kellner, James D., Kleynhans, Jackie, Knol, Mirjam J., Kozakova, Jana, Kristinsson, Karl G., Ladhani, Shamez N., MacDonald, Laura, Mackenzie, Grant A., Mad'arová, Lucia, McGeer, Allison, Mereckiene, Jolita, Morfeldt, Eva, Mungun, Tuya, Muñoz-Almagro, Carmen, Nuorti, J. Pekka, Paragi, Metka, Pilishvili, Tamara, Puentes, Rodrigo, Saha, Samir K., Sahu Khan, Aalisha, Savrasova, Larisa, Scott, J. Anthony, Skoczy?ska, Anna, Suga, Shigeru, van der Linden, Mark, Verani, Jennifer R., von Gottberg, Anne, Winje, Brita A., Yildirim, Inci, Zerouali, Khalid, Hayford, Kyla, The Pserenade Team |
Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 Following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project |
Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antige... |
2021 |
9 |
Ver Más |
Staadegaard, Lisa, Caini, Saverio, Wangchuk, Sonam, Thapa, Binay, de Almeida, Walquiria Aparecida Ferreira, de Carvalho, Felipe Cotrim, Fasce, Rodrigo A., Bustos, Patricia, Kyncl, Jan, Novakova, Ludmila, Caicedo, Alfredo Bruno, de Mora Coloma, Domenica Joseth, Meijer, Adam, Hooiveld, Mariëtte, Huang, Q. Sue, Wood, Tim, Guiomar, Raquel, Rodrigues, Ana Paula, Lee, Vernon Jian Ming, Ang, Li Wei, Cohen, Cheryl, Moyes, Jocelyn, Larrauri, Amparo, Delgado-Sanz, Concepción, Demont, Clarisse, Bangert, Mathieu, Dückers, Michel, van Summeren, Jojanneke, Paget, John |
Defining the seasonality of respiratory syncytial virus around the world: National and subnational surveillance data from 12 countries |
BACKGROUND: Respiratory syncytial virus (RSV) infections are one of the leading causes of lower respiratory tract infections and have a major burden on society. For prevention and control to be deploy... |
2021 |
15 |
Ver Más |
Castellucci, Héctor Ignacio, Viviani, Carlos, Hernández, Paulina, Bravo, Gonzalo, Martínez, Marta, Ibacache, Jaime, Bartsch, Ángelo |
Developing countries and the use of ISO Standard 11228-3 for risk management of Work-Related Musculoskeletal Disorders of the Upper Limbs (WRMSDs-ULs): The case of Chile |
Work-Related Musculoskeletal Disorders of the Upper Limbs (WRMSDs-ULs) are one of the most common occupational diseases worldwide. Repetitive motion is one of the main risk factors associated with the... |
2021 |
96 |
Ver Más |
Teresa Valenzuela, María, Urquidi, Cinthya, Rodriguez, Nicolás, Castillo, Luis, Fernández, Jorge, Ramírez, Eugenio |
Development of neutralizing antibody responses against SARS-CoV-2 in COVID-19 patients |
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19) are new global problems. The understanding of the host immune response in COV... |
2021 |
93 |
Ver Más |
Aburto, A., Zapata, D., Retamales, E., Moscoso, H., Canales, C., Escobar, C. |
Erythrocyte antigens and antibodies in the Chilean population |
Chile does not have a national registry of immunohematologic test results, there are no data on the prevalence of erythrocyte antigens and the frequency of antibodies in this population. Therefore, fo... |
2021 |
37 |
Ver Más |
Wang, Xin, Li, You, Deloria-Knoll, Maria, Madhi, Shabir A., Cohen, Cheryl, Ali, Asad, Basnet, Sudha, Bassat, Quique, Brooks, W. Abdullah, Chittaganpitch, Malinee, Echavarria, Marcela, Fasce, Rodrigo A., Goswami, Doli, Hirve, Siddhivinayak, Homaira, Nusrat, Howie, Stephen R. C., Kotloff, Karen L., Khuri-Bulos, Najwa, Krishnan, Anand, Lucero, Marilla G., Lupisan, Socorro, Mira-Iglesias, Ainara, Moore, David P., Moraleda, Cinta, Nunes, Marta, Oshitani, Histoshi, Owor, Betty E., Polack, Fernando P., O'Brien, Katherine L., Rasmussen, Zeba A., Rath, Barbara A., Salimi, Vahid, Scott, J. Anthony G., Simões, Eric A. F., Strand, Tor A., Thea, Donald M., Treurnicht, Florette K., Vaccari, Linda C., Yoshida, Lay-Myint, Zar, Heather J., Campbell, Harry, Nair, Harish, Respiratory Virus Global Epidemiology Network |
Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study |
BACKGROUND: Human metapneumovirus is a common virus associated with acute lower respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs associated with human met... |
2021 |
9 |
Ver Más |